Labor Secretary Lori Chavez-DeRemer resigned her post on April 20, 2026, the White House confirmed, marking her exit from President Trump's cabinet amid a reported misconduct investigation. The resignation was acknowledged across outlets spanning the political spectrum, making it one of the more notable cabinet departures of the second Trump administration.

Chavez-DeRemer, a former Republican congresswoman from Oregon, had been considered a relatively moderate pick for the Labor Secretary role at the time of her confirmation. Her selection had drawn attention partly due to her prior record of supporting some union-backed legislation, which made her an unusual choice for a Republican administration.

Details surrounding the nature of the misconduct investigation have not been fully disclosed by the White House. The administration did not immediately provide a detailed explanation of the circumstances leading to her departure, and it remains unclear whether she resigned voluntarily or under pressure.

Her exit adds to a pattern of turnover within Trump's second-term cabinet. Multiple administration officials have departed since the start of the term, prompting questions about internal stability at senior levels of the executive branch. No immediate announcement was made regarding a replacement or acting secretary.