Israeli warplanes struck two nuclear-related facilities and two of Iran's largest steel plants on Friday, marking a significant escalation in the five-week-old conflict. The targets included the Shahid Khondab Heavy Water Complex at the Arak nuclear site in central Iran and the Ardakan yellowcake uranium production plant in Yazd Province, as well as the Khuzestan Steel facility near Ahvaz and the Mobarakeh Steel complex in Isfahan — two of Iran's largest industrial employers. Iran's Atomic Energy Organization confirmed the nuclear facilities were struck; no casualties were reported and Iranian officials said there was no risk of radiation contamination. PBS NewsHour, Bloomberg, and Fortune all confirmed the scope of Friday's strikes.

Israeli Defense Minister Israel Katz declared that the strikes were a direct response to Iranian attacks on Israeli cities and announced further escalation: "Attacks in Iran will escalate and expand to additional targets and areas that assist the regime in building and operating weapons against Israeli citizens." An IRGC commander issued a pointed warning in return: "This time, the equation will no longer be an eye for an eye — just wait." Iranian Foreign Minister Abbas Araghchi said Iran would exact a heavy price for the Israeli strikes. Iranian state media reported that air raid sirens sounded across Tel Aviv and other Israeli cities overnight as Iran and Hezbollah launched retaliatory missile and drone attacks; Israeli media reported at least 25 people were wounded in northern Israel from a Hezbollah rocket strike on Nahariya.

The strikes came as President Trump simultaneously claimed ceasefire negotiations were going very well and extended Iran's deadline to reopen the Strait of Hormuz to April 6. Trump delivered a 15-point peace proposal to Tehran via Pakistan as an intermediary. Iran's government publicly rejected the proposal, countering with a five-point plan of its own demanding reparations and recognition of Iranian sovereignty over the strait. The gap between the two sides' stated positions remains substantial, with analysts noting the maximum Iran might be willing to give does not meet the minimum the U.S. is demanding.

The Arak heavy-water complex has long been a central concern for Western governments and nonproliferation experts because heavy-water reactors can produce weapons-usable plutonium as a byproduct of operation. The Ardakan yellowcake plant processes uranium ore into a form suitable for further enrichment. The strikes represented Israel's most direct action against nuclear-related infrastructure since the start of the conflict. Analysts said the strikes do not appear to have eliminated Iran's nuclear knowledge or capabilities, but they destroyed physical infrastructure and sent a signal about the breadth of future Israeli targeting.