The U.S. Senate began floor debate on March 17 on the SAVE America Act — the Safeguard American Voter Eligibility Act — after a 51-48 procedural vote cleared the way for debate over the objections of unified Democrats and Sen. Lisa Murkowski of Alaska. The bill, which passed the House 218-213 on February 11, would require Americans to present documentary proof of U.S. citizenship — such as a passport or birth certificate — to register to vote in federal elections, and would require photo identification to cast ballots, including by mail. It would also authorize the Department of Homeland Security to flag suspected non-citizens on state voter rolls for disqualification. Fox News covered the Senate debate launch with a live news blog headlined "Trump battles GOP holdouts and Democrats amid SAVE America Act Senate test vote," while CNN reported the Senate had "kicked off a marathon debate" over the bill.

Trump publicly pressured Senate Republican holdouts and called mail-in voting "corrupt" as debate began. Fox News reported the president's statements alongside Majority Leader John Thune's position that the bill's core requirements — proof of citizenship to register and ID to vote — are "overwhelmingly popular all across this country, no matter what your political party is." Senate Republicans acknowledged they lack the 60 votes needed to overcome a filibuster and end debate, but promised to keep the Senate floor occupied with debate to force Democrats on record on the issue. CNBC confirmed the 51-48 procedural vote on March 17 and noted the bill's dim prospects for overcoming the 60-vote threshold.

On March 21, CNN published a new poll showing Americans are meaningfully divided on the bill's core premise. The survey found that 43 percent of Americans believe the citizenship registration requirement would "mostly prevent illegal noncitizen voting," but 57 percent said it would "mostly prevent legal citizens from voting" (29 percent) or would affect both groups about equally (28 percent). The survey also found 42 percent of Americans consider ineligible voting a "major problem," while roughly the same share — 44 percent — say preventing eligible citizens from voting is equally a "major problem." Among Republicans, 49 percent said noncitizen voting happens "a lot," while the other 51 percent said it happens "sometimes" or less. NPR reported on March 19 that several Republican-led states, including Florida, have begun passing their own state-level SAVE Act equivalents in anticipation of federal inaction.

Democratic opponents of the bill, cited by NBC News, argue more than 21 million Americans lack the documents required to register under the legislation, and that married women who have changed their last names would face particular bureaucratic barriers. PolitiFact reported on March 19 that the name-change issue disproportionately affects women. The White House countered by citing multiple polls it said showed 80-plus percent support for voter ID requirements, including majorities of Democratic and minority voters. FactCheck.org published a detailed Q&A on March 21 examining competing claims about the bill, finding that while voter ID is broadly popular in abstract polling, the specific documentary proof-of-citizenship requirement is more divisive and that documented noncitizen voting in federal elections is rare.