Negotiations between the United States and Iran concluded in Pakistan on Saturday without a deal, Vice President JD Vance confirmed, after the two sides engaged in more than 21 hours of direct talks. The sessions, which stretched past midnight, were described as among the most significant diplomatic contact between Washington and Tehran in years.

Vance stated that the talks ended without an agreement, indicating that Iran had not met the conditions the American side required to move forward. The extended length of the negotiations reflected the complexity of the issues on the table, though neither side provided detailed accounts of the specific sticking points that prevented a resolution.

The choice of Pakistan as a neutral host underscored the diplomatic sensitivity of the engagement. Officials characterized the discussions as substantive, even as they acknowledged the failure to produce a concrete outcome. The prolonged duration of the sessions suggested both delegations made efforts to bridge their differences before ultimately breaking off without an accord.

The breakdown leaves the broader question of Iran's nuclear program and regional tensions unresolved. Analysts noted that while the absence of a deal represents a setback, the willingness of both governments to engage in extended direct talks was itself a notable development in a relationship defined for decades by hostility and indirect communication.

No timeline was immediately announced for a resumption of negotiations. Both governments were expected to assess the outcome before signaling whether further talks remain possible.